Prontosil etc. in Puerperal Streptococcus Infections

Chemotherapy in Acute Surgical Infections with Prontosil and Allied Drugs

Prontosil in Obstetrics

Hospital for cases of puerperal fever. The results ^ere encouraging, especially in cutting short the Pyrexial period. I later used it for the same purpose at Ham Green Hospital, and afterwards at the General Hospital. The improvement in the mortality rate ^ras not obvious, as the number of cases treated was too small for comparison with those treated before the introduction of Prontosil. The mo...

Prontosil Album in Gangrenous Stomatitis

A male child, aged about 10 years, was admitted for frequency of stools with blood and mucus for 20 days, following an attack of measles. The patient was extremely emaciated with subnormal temperature and pulse about 120 per minute. Stools, 20 to 30 in a day, consisted of only blood and mucus. Treatment with emetine, kaolin, bismuth and rectal washes caused the frequency of stools greatly to di...

Host-pathogen interactions in Streptococcus pyogenes infections, with special reference to puerperal fever and a comment on vaccine development.

Streptococcus pyogenes (group A streptococcus) causes a variety of diseases, including acute pharyngitis, impetigo, rheumatic fever and the streptococcal toxic shock syndrome. Moreover, S. pyogenes was responsible for the classical example of a nosocomial infection, the epidemics of puerperal fever (childbed fever) that caused the death of numerous women in earlier centuries. The most extensive...

Puerperal fever, the streptococcus, and the sulphonamides, 1911-1945.